Application
detection of bioavailable copper in serum for diagnostic purposes
- Urgent need for ultrasensitive analyte detection in the diagnosis of various diseases, e.g. Cu-detection for Wilsons Disease and Alzheimers' Disease
- Need for flexible bed-side diagnostics
- Demand for low-cost mobile solutions for analyte detection for environmental samples
There is a clear need for improved precision for detection of bioavailable copper in serum for diagnostic purposes
Cu-sensor
- Medical Applications
- Wilsons Disease
- Alzheimers' Disease
ultrasensitive detection of bioavailable copper in serum and urine
Nanopore-based detection of bioavailable “free” Cu(II)
Two different detection principals are employed:
1. Fluorescence detection with a range of 13.5 nM- 60 µM
2. Ion Flow (I-V) detection with a sensitivity down to 10 femto molar Cu(II) concentrations , linear over seven orders of magnitude
(PCT application has been filled in January 2019 – currently in national phase EU, USA)